microRNA cluster MC-let-7a-1~let-7d promotes autophagy and apoptosis of glioma cells by down-regulating STAT3.

CONCLUSION: Taken together, the miR cluster MC-let-7a-1 ~ let-7d promotes glioma cell autophagy and apoptosis by repressing STAT3. The current study highlights the potential of the miR cluster MC-let-7a-1 ~ let-7d as biomarkers and promising treatment strategies for glioma. PMID: 31868319 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31868319?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - December 22, 2019 Category: Neuroscience Authors: Yang ZY, Wang Y, Liu Q, Wu M Tags: CNS Neurosci Ther Source Type: research