LncRNA TUG1 mediates ischemic myocardial injury by targeting miR-132-3p/HDAC3 axis.

CONCLUSIONS: The TUG1/miR-132-3p/HDAC3 axis critically regulates ROS production and the pathogenic development of AMI. Targeting TUG1, up-regulating miR-132-3p, or inhibiting HDAC3 may benefit AMI treatment. PMID: 31858814 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31858814?dopt=Abstract

Source: American Journal of Physiology. Heart and Circulatory Physiology - December 19, 2019 Category: Physiology Authors: Su Q, Liu Y, Lv XW, Dai RX, Yang XH, Kong BH Tags: Am J Physiol Heart Circ Physiol Source Type: research