GWAS studies reveal a possible genetic link between cancer and suicide attempt - Voskarides K, Chatzittofis A.

Inuit is the population with the highest incidence of suicide attempt and cancer in the world. Previous studies reported that people attempted suicide have a higher future risk for cancer. In view of these data, the largest available genome wide associatio...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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Meaningful progress towards the control of cancer, ending it as a major threat to life and health, will be led by programs that can produce very broadly applicable treatments. That means therapies that can be applied to many (or even all) cancers with minimal differences in configuration or need for further per-cancer development. There are hundreds of cancer subtypes, but only so many researchers, and only so much funding for research and development: development of highly specific therapies is just not an effective path forward. Examples of the most promising lines of work with broad application include the OncoSe...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
As a cause of excess mortality, socioeconomic disadvantage rivals smoking, hypertension, cancer, and cardiovascular disease. At age 40 years, the poorest US women can expect to die about a decade sooner than the richest; for men the gap is 15 years. Socioeconomic inequalities are so pervasive that it is easy to assume they are immutable. Historical evidence demonstrates that tremendous progress toward narrowing inequalities is possible. Unfortunately, recent trends in the United States indicate that it is also possible to exacerbate inequalities: gaps in adult life expectancy have grown ever-larger since the 1980s. Decline...
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work. Kimera Labs ...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
ConclusionsDeaths from primary cancer remain a major concern; however, follow ‐up is required for both cancer and noncancer‐related health issues in cancer survivors, especially concerning suicide and cardiovascular deaths.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Most people know about the damaging effects that binge drinking can bring to someone’s life. Loss of enjoyment of life, losing family relationships, financial and career struggles, homelessness, and legal consequences are just the tip of the iceberg. However, it can be more difficult to realize the long-term effect of binge drinking on the body, because you cannot always see it. Frequent binge drinking poses many dangerous health risks, and many of them can lead to death. Facts on Long-Term Effect of Binge Drinking on the Body For men, binge drinking is defined as consuming five or more drinks within about two hour...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol dependence alcohol treatment alcohol treatment center binge binge drinking Source Type: blogs
BACKGROUND: Many researchers have studied suicide risk factors of patients with one specific cancer. But there is no comprehensive study to compare suicide issues between adolescents and young adult (AYA) group and all-age groups in a pan-cancer view. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Is your alcohol use turning into something you are worried about? It can be hard for many people to determine whether or not they have a problem with alcohol, but chances are, you’re not happy with your current drinking habits. If you’re wondering “do I have an alcohol problem?’, keep reading for a few tell-tale signs, what is involved with treatment, and what can happen if you leave your alcohol problem untreated. Ask Yourself These Questions If you are asking yourself, “do I have an alcohol problem?”, as yourself the following questions first. If you answer yes to most or all of them,...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol abuse alcohol detox alcohol treatment Source Type: blogs
CONCLUSIONS: The majority of doctors perform symptom control in terminally ill patients. PAS is frequently requested but rarely carried out. Attending physicians felt the legal situation was ambiguous. Physicians should therefore receive training in current legislation relating to end-of-life choices and medical decisions. The data collected in this survey will help political decision-makers provide the necessary legal framework for end-of-life medical care. PMID: 31901225 [PubMed - in process]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: BMC Palliat Care Source Type: research
Mutational damage to nuclear DNA occurs constantly in all cells, and not all of it is successfully repaired. Setting aside recent evidence for cycles of damage and repair to cause epigenetic changes characteristic of aging, most unrepaired mutational damage has no meaningful consequence. It occurs in somatic cells that have few cell divisions left, so will not spread, and these cells will die or become senescent and be destroyed once they reach the Hayflick limit. It occurs in genes that are not active in the tissue in question, so even in long-lived somatic cells that do not replicate, such as those of the central nervous...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
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