Non-ischemic Cardiomyopathy: Role of Immunologic Work-up and Cardiac MRI in Etiologic Diagnosis and Outcomes.

Non-ischemic Cardiomyopathy: Role of Immunologic Work-up and Cardiac MRI in Etiologic Diagnosis and Outcomes. J Assoc Physicians India. 2019 Dec;67(12):30-34 Authors: Malgutte D, Waghmare I, Bhute V, Joshi A, Gokhale Y Abstract Objective: Study etiology of Non ischemic cardiomyopathy (NICMP) and role of cardiac MRI in diagnosis and outcomes. Methods: prospective observational study. Inclusion Criteria: 1. Clinical feature of cardiac failure, 2. 2D ECHO Systolic dysfunction, EF <45% OR Diastolic dysfunction without regional wall motion abnormality, 3. Absent ischemic changes on ECG and/ or coronary angiography. Exclusion: Valvular & congenital heart disease, Cor pulmonale, Renal failure. Patient were subjected to CBC with absolute eosinophil count(AEC), ESR, Urine-r/m, NT-Pro-BNP, ANA, ANCA, ACE, Bone marrow, Amyloid fat pad biopsy etc., chest x ray, 2DE. HRCT Chest and coronary angiography, Cardiac MRI by 3 tesla MRI machine. Patients were treated with antic-failure drugs & as per etiology and followed at 6wk clinically (NYHA) and 2DE. Result: forty four Patients, mean age 36 yrs F: M(22:22), many patients had feature other than cardiac failure like Raynaud's. PMID: 31801327 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research