Bioprofiles and mechanistic pathways associated with Cheyne-Stokes respiration: insights from the SERVE-HF trial

ConclusionWe identified proteomic signatures that may represent underlying mechanistic pathways associated with patterns of CSR in HFrEF. These hypothesis-generating findings require further investigation towards better understanding of CSR in HFrEF.Graphic abstractSummary of the findings.PAR-1 proteinase-activated receptor 1,ADM adrenomedullin,HSP-27 heat shock protein-27,ITGB2 integrin beta 2,GLO1 glyoxalase 1,ENRAGE/S100A12 S100 calcium-binding protein A12,LOX-1 lectin-like LDL receptor 1,ADAM-TS13 disintegrin and metalloproteinase with a thrombospondin type 1 motif, member13 also known as von Willebrand factor-cleaving protease.
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research