MicroRNA-26a Promotes Tumor Growth and Angiogenesis in Glioma by Directly Targeting Prohibitin.

CONCLUSION: These results reveal that miR-26a regulates PHB and promotes glioma progression both in vitro and in vivo and that miR-26a and its target PHB are associated with glioma development, which can be helpful in developing microRNA-based treatment for glioma in the future.
PMID: 23870455 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - July 22, 2013 Category: Neuroscience Authors: Qian X, Zhao P, Li W, Shi ZM, Wang L, Xu Q, Wang M, Liu N, Liu LZ, Jiang BH Tags: CNS Neurosci Ther Source Type: research