Response of pearl oyster Pinctada fucata martensii to allograft-induced stress from lipid metabolism

Publication date: Available online 14 November 2019Source: Fish &Shellfish ImmunologyAuthor(s): Chengzhang He, Ruijuan Hao, Yuewen Deng, Chuangye Yang, Xiaodong DuAbstractThe pearl oyster, Pinctada fucata martensii, produces high-quality pearls. During pearl production, excess immune and inflammatory response after transplantation will lead to nucleus rejection, pearl sac formation failure, and death of the host pearl oyster. The hemocyte transcriptome and fatty acid (FA) contents in the adductor muscle before and after transplantation were analyzed to investigate the response of pearl oyster P. f. martensii to allograft-induced stress from lipid metabolism. The hemocyte transcriptome analysis detected 193 lipid metabolism-related genes, such as the elongation of very long-chain FA protein 5, acyl-CoA 6-desaturase, cytochrome P450, phospholipase A2, glycerol-3-phosphate O-acyltransferase, and prostaglandin-H2 d-isomerase. Pathway enrichment analyses revealed that these genes were mainly involved in the “biosynthesis of unsaturated FAs,” “FA biosynthesis,” “ARA metabolism,” and “glycerolipid metabolism.” An analysis of FA contents in the adductor muscle indicated no significant difference in the contents of lauric acid, myristic acid, pentadecanoic acid, palmitic acid, palmitoleic acid, heptadecanoic acid, stearic acid, oleic acid, vaccenic acid, linoleic acid, arachidic acid, α-linolenic acid, eicosadienoic acid, docos...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research

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