IJERPH, Vol. 16, Pages 4489: Quadrivalent Influenza Vaccine-Induced Antibody Response and Influencing Determinants in Patients ≥ 55 Years of Age in the 2018/2019 Season
Conclusions: QIV was immunogenic against the additional B lineage strain (B Victoria) without significantly compromising the immunogenicity of the other three vaccine strains, therefore, adding a second B lineage strain in QIV could broaden protection against influenza B infection in this age group. As the QIV immunogenicity differed regarding the four antigens, formulation adjustments to increase the antigen concentration of the serotypes that have lower immunogenicity could increase effectiveness. Prior season vaccination was associated with lower antibody response to a new vaccine, although not consistent through the vaccine strains.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Maria Ganczak Paulina Dubiel Marzena Drozd-D ąbrowska Ewelina Hallmann-Szeli ńska Karol Szyma ński Lidia B. Brydak Tags: Article Source Type: research
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