Biosynthesis and characterization of silver nanoparticles capped by biomolecules by fumaria parviflora extract as green approach and evaluation of their cytotoxicity against human breast cancer MDA-MB-468 cell lines

This study tried to prepare AgNPs from AgNO3 solution as Ag precursor and Fumaria parviflora (Fp) extract as stabilizing and reducing agents. The anticancer activity of the final product has been studied using human breast cancer cells. Characterization of final products were carried out using UV–visible spectrum, dynamic light scattering (DLS), zeta potential, Fourier transform infrared Spectroscopy (FTIR), X-Ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) techniques. As a result, well-dispersed spherical AgNPs (with the size of lower than ~40 nm) have been successfully prepared in this study. Also, 3-(4,-5-dimethylthiazol-2-yl)-2-5-diphenyltetrazolium bromide (MMT) results showed that the green synthesized of FpAgNPs can be used as potential anticancer nanodrugs with the strong cytotoxic activity.
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research