Dysregulation of liver developmental microRNA contribute to hepatic carcinogenesis.

CONCLUSIONS: Dysregulation of liver developmental miRNAs, which exert a tumor suppressant effect, in EpCAM-positive HpSCs may contribute to liver carcinogenesis by promoting the transformation of HpSCs to CSCs of HB and HCC.
PMID: 31627983 [PubMed - as supplied by publisher]

Source: J Formos Med Assoc - October 14, 2019 Category: General Medicine Authors: Wu JF, Ho MC, Ni YH, Hsu HY, Lee PH, Chang MH Tags: J Formos Med Assoc Source Type: research