Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma.

CONCLUSION: The methylation levels ofPAX1, SOX1 and ZNF582 genes were all higher in cancer tissues than in paired-adjacent and normal tissues, suggesting that detection of PAX1/SOX1/ZNF582 methylation status may serve as a promising biomarker for ESCC screening and diagnosis.
PMID: 31629253 [PubMed - as supplied by publisher]

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 15, 2019 Category: Drugs & Pharmacology Authors: Tang L, Liou YL, Wan ZR, Tang J, Zhou Y, Zhuang W, Wang G Tags: Biomed Pharmacother Source Type: research