Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso

Conclusions/SignificanceThe current study provides further evidence of a human reservoir for invasive non-Typhoidal Salmonella (iNTS) in sub-Saharan Africa.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research

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Analyst, 2020, Accepted Manuscript DOI: 10.1039/C9AN02011J, PaperLinlin Zhuang, Jiansen Gong, Yongxin Ji, Peilong Tian, Fei Kong, Huiyuan Bai, Ning Gu, Yu Zhang Salmonella spp. are zoonotic pathogens of substantial public health concern. To enable detection in the field or instrument-free conditions, we developed a rapid and robust lateral flow fluorescent immunoassay based... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
In conclusion, cows and buffaloes act as reservoirs ofSalmonella infection in dairy farms in Egypt and contribute a risk of zoonotic transmission to human.
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
In this study, paeonol was identified as an inhibitor of the S. Typhimurium T3SS. Paeonol significantly blocked the translocation of SipA into host cells and suppressed the expression of effector proteins without affecting bacterial growth in the effective concentration range. Additionally, S. Typhimurium-mediated cell injury and invasion levels were significantly reduced after treatment with paeonol, without cytotoxicity. Most importantly, the comprehensive protective effect of paeonol was confirmed in an S. Typhimurium mouse infection model. Preliminary mechanistic studies suggest that paeonol inhibits the expression of ...
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research
(European Centre for Disease Prevention and Control (ECDC)) Nearly one in three foodborne outbreaks in the EU in 2018 were caused by Salmonella. This is one of the main findings of the annual report on trends and sources of zoonoses published by the European Food Safety Authority (EFSA) and the European Centre for Disease Prevention and Control (ECDC). West Nile virus and STEC infections were reported at unusually high levels.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
In this study, we evaluated the efficacy of our two previously developed real time-quantitative PCR (qPCR) assays for the detection of swine-associated Bacteroidales genetic markers (gene 1–38, gene 3–53) in the Yangtze Delta watershed of southeastern China. The results indicated that the gene 1–38 and 3-53 markers exhibited high accuracy (92.5%, 91.7% conditional probability, respectively) in detecting Bacteroidales spp. in water samples. According to binary logistic regression (BLR), these two swine-associated markers were well correlated (P 
Source: Journal of Environmental Sciences - Category: Environmental Health Source Type: research
Publication date: Available online 5 December 2019Source: Research in Veterinary ScienceAuthor(s): Marta Perez-Sancho, Teresa García-Seco, Concepción Porrero, Nerea García, Susana Gomez-Barrero, Jose María Cámara, Lucas Domínguez, Julio ÁlvarezAbstractFeral pigeons have increased in urban settings worldwide becoming a potential health risk for humans and other animals. Control and surveillance programs are essential to prevent the possible transmission of zoonotic pathogens carried by pigeons. A surveillance program was carried out in Madrid City (Spain) during 2005–20...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
AbstractSalmonella enterica is a veterinary and zoonotic pathogen of global importance. While murine and cell-based models of infection have provided considerable knowledge about the molecular basis of virulence ofSalmonella, relatively little is known about salmonellosis in naturally-affected large animal hosts such as cattle, which are a reservoir of human salmonellosis. As in humans,Salmonella causes bovine disease ranging from self-limiting enteritis to systemic typhoid-like disease and exerts significant economic and welfare costs. Understanding the nature and consequences ofSalmonella interactions with bovine cells w...
Source: Veterinary Research - Category: Veterinary Research Source Type: research
In this study, sixty significant differentially expressed genes were screened between susceptible and resistant sheep macrophages by transcriptome RNA-seq. Eight significantly enriched GO terms and six canonical pathways were involved by GO and KEGG enrichment analysis. Furthermore, the function of HMOX1, SLPI and SPP1 was verified by siRNA, which the knockdown of HMOX1 and SLPI increased remarkably the clearance of S. typhimurium, but SPP1 had little effect on the clearance of S. Typhimurium within sheep macrophages. Altogether, these results suggest that many genes of macrophages were reprogrammed via S. Typhimurium infe...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
(BfR Federal Institute for Risk Assessment) To make food even safer for humans, experts from scientific institutions, food regulatory authorities and the business community will discuss current developments and strategies at the 'Zoonoses and Food Safety' Symposium at the German Federal Institute for Risk Assessment (BfR) on 4 and 5 November 2019, in Berlin-Marienfelde. Because some micro-organisms in food can cause health problems. Campylobacter in raw milk, salmonella in eggs or listeria in ready-to-eat foods often lead to outbreaks affecting numerous patients.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Publication date: March 2020Source: Food Control, Volume 109Author(s): Cathrine F. Kure, Lars Axelsson, Mats Carlehög, Ingrid Måge, Merete R. Jensen, Askild HolckAbstractSalmonella and Campylobacter represent the two most commonly reported zoonoses in EU and cause a significant health burden. The effects of a prototype steam treatment system (Deconizer) on reduction of aerobic bacteria, Salmonella Enteritidis and Campylobacter jejuni on chicken carcasses were investigated in the present study. In addition, the treated chicken carcasses were subjected to sensory analysis. The system tested is intended to be integ...
Source: Food Control - Category: Food Science Source Type: research
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