Fluorouracil, Doxorubicin, and Cyclophosphamide (FAC) Versus FAC Followed by Weekly Paclitaxel As Adjuvant Therapy for High-Risk, Node-Negative Breast Cancer: Results From the GEICAM/2003-02 Study.

CONCLUSIONFor patients with high-risk node-negative BC, the adjuvant FAC-wP regimen was associated with a small but significant improvement in DFS compared with FAC therapy, in addition to manageable toxicity, especially regarding long-term cardiac effects.
PMID: 23733779 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - June 3, 2013 Category: Cancer & Oncology Authors: Martín M, Ruiz A, Borrego MR, Barnadas A, González S, Calvo L, Vila MM, Antón A, Rodríguez-Lescure A, Seguí-Palmer MA, Muñoz-Mateu M, Ribugent JD, López-Vega JM, Jara C, Espinosa E, Fernández CM, Andrés R, Ribelles N, Plazaola A, Sánchez-Rovira Tags: J Clin Oncol Source Type: research