Microglia and astroglia proliferation within the normal appearing white matter in histologically active and inactive multiple sclerosis.

CONCLUSIONS: Our results suggest that within MS NAWM, which appears to be involved at the very least, intense diffuse micro- and astroglia reactions occur. Possibly, microglia rather support proinflammatory mechanisms, whereas astrocytes seem to be more neuroprotective. Diffuse microglia proliferation indicates that CNS immune system is chronically activated within the whole CNS. PMID: 31588711 [PubMed - in process]
Source: Folia Neuropathologica - Category: Neurology Tags: Folia Neuropathol Source Type: research