Neurophysiological and Psychological Predictors of Social Functioning in Patients with Schizophrenia and Bipolar Disorder.

CONCLUSION: Our results implicated that even though each group has different predictors of social functioning, early traumatic events and HRV could be important indicators of functional outcome irrespective of what group they are. PMID: 31587532 [PubMed - as supplied by publisher]
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research

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Authors: Barton BB, Segger F, Fischer K, Obermeier M, Musil R Abstract Introduction: Antipsychotic-induced weight-gain (AIWG) is a very important, yet often neglected side-effect in the treatment with first and second generation antipsychotics. AIWG can increase the risk of developing metabolic syndrome, diabetes and cardiovascular disease. Meta-analyses mostly concentrate on AIWG in schizophrenic and bipolar patients, even though antipsychotics are prescribed off-label across many other diagnostic groups (e.g. anxiety disorders, depression, autistic disorder).Areas covered: Pub Med and Web of Science were systemat...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
In this study, patients didn’t need a smartphone[PM1] . It could be simple and low tech on the patient end, and high tech on the backend.”Researchers hope that artificial intelligence that can analyze data collected from apps such as My Coach Connect will enable more proactive and personalized care for individuals. The application, for example, may help improve treatment by intervening early when someone is experiencing more symptoms.“Artificial intelligence allowed us to illuminate the various clinically meaningful dimensions of language use and vocal patterns of the patients over time and pers...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
INTRODUCTION: Schizophrenia, bipolar disorder and schizoaffective disorders are severe mental illnesses (SMI) associated with high levels of co-morbid psychopathology and premature mortality. Reducing delays in accessing services and providing early interv...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: April 2020Source: Materials Science and Engineering: C, Volume 109Author(s): Renuka S. Managuli, Julie Tzu-Wen Wang, Farid Muhammad Faruqu, Abhjieet Pandey, Sanyog Jain, Khuloud T. Al-Jamal, Srinivas MutalikAbstractAsenapine maleate (ASPM) is an antipsychotic drug prescribed for the treatment of schizophrenia and bipolar disorder. ASPM possesses low oral bioavailability due to extensive hepatic metabolism. Therefore, RGD peptide conjugated liposomes loaded with ASPM were prepared to target Peyer's patches in the intestine which in-turn get access into intestinal lymphatic system thereby increasing the ora...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
ConclusionPsychotropic medication non-adherence was high. It was influenced by various factors operating at different levels. Therefore, comprehensive intervention strategies should be designed to address factors associated with psychotropic medication non-adherence.Systematic review registrationPROSPERO CRD42017067436
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Astudy appearing today inJAMA Psychiatry found that fewer than 7% of patients with psychiatric disorders in Sweden had either been subjected to violence severe enough to require specialist medical treatment or had perpetrated violence.Amir Sariaslan, Ph.D., of the University of Oxford and colleagues identified 250,419 individuals from Sweden ’s National Patient Register who were born between 1973 and 1993 and had been diagnosed psychiatric disorders. Psychiatric disorders included anxiety disorders, depression, bipolar disorder, schizophrenia, personality disorders, alcohol use disorder, and drug use disorder. The pa...
Source: Psychiatr News - Category: Psychiatry Tags: Amir Sariaslan anxiety bipolar disorder depression JAMA Psychiatry Paul Appelbaum personality disorders schizophrenia substance use disorder violence Source Type: research
DiscussionCACNA1C rs11615998 was associated with psychotic symptoms (C-allele carriers have decreased psychotic-risk) independently from the diagnosis, in line with the evidence of a cross disorder effect of many risk variants. This gene was previously associated with SCZ and cross-disorder liability to psychiatric disorders. Our findings confirmed that deep phenotyping is pivotal to clarify the role of genetic variants on symptoms patterns.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 13 January 2020Source: Pharmacology Biochemistry and BehaviorAuthor(s): Indrani Poddar, Patrick M. Callahan, Caterina M. Hernandez, Anilkumar Pillai, Xiangkun Yang, Michael G. Bartlett, Alvin V. TerryAbstractAntipsychotic drugs (APDs) are essential for the treatment of schizophrenia and other neuropsychiatric illnesses such as bipolar disease. However, they are also extensively prescribed off-label for many other conditions, a practice that is controversial given their potential for long-term side effects. There is clinical and preclinical evidence that chronic treatment with some APDs ma...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Publication date: Available online 13 January 2020Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Elisa C. Santa Cruz, Katherine C. Madrid, Marco A.Z. Arruda, Alessandra SussuliniAbstractBackgroundImbalances in metal concentrations have been suggested to contribute to the pathophysiology of different brain disorders, such as bipolar disorder (BD) and schizophrenia (SCZ).ObjectivesThe aim of this exploratory study is to evaluate the association between the concentrations of macro/trace elements in serum from BD and SCZ patients considering the effects from different treatments.MethodsEleven subjects with...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
In this report we describe a 12p13.33 micro-deletion involving one coding gene only, in contrast with previous studies that mostly concluded that a multi-genes deletion in the 12p13.33 sub-telomeric region is responsible of the minimum clinical phenotype of patients with 12p13.33 monosomy. Certainly, larger deletions spanning multiple Mb in 12p13.33 are responsible for more severe phenotypes, associated to a variable degree of dysmorphic features. PMID: 31953239 [PubMed - as supplied by publisher]
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Eur J Med Genet Source Type: research
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