Prophylaxis of Experimental Endocarditis With Antiplatelet and Antithrombin Agents: A Role for Long-term Prevention of Infective Endocarditis in Humans?

Conclusions. Antiplatelet and direct antithrombin agents may be useful in the prophylaxis of IE in humans. In particular, the potential dual benefit of dabigatran etexilate might be reconsidered for patients with prosthetic valves, who require life-long anticoagulation and in whom S. aureus IE is associated with high mortality.

Source: The Journal of Infectious Diseases - December 12, 2014 Category: Infectious Diseases Authors: Veloso, T. R., Que, Y.-A., Chaouch, A., Giddey, M., Vouillamoz, J., Rousson, V., Moreillon, P., Entenza, J. M. Tags: BACTERIA Source Type: research