Benzocaine: Review on a Drug with Unfold Potential.

Benzocaine: Review on a Drug with Unfold Potential. Mini Rev Med Chem. 2019 Sep 13;: Authors: Khair-Ul-Bariyah S, Ali M, Din MI, Sharif A, Ahmed E, Arshad M Abstract Benzocaine has been well-known for its role as anesthetic agent and largely used in oral ulcers, ear pain and dental complications. Along with lidocaine and other local anesthetics, benzocaine has marked its part as an anesthetic in surgical procedures and as Na+ channels blocker, as well. Analogues of benzocaine have been found to possess biological potentials including antibacterial antifungal and anti-cancer. Some derivatives were found to have conspicuous action against tuberculosis. Current review focuses to explore the century long potential of the molecule and its analogs that have appeared in the literature. Further to this, highlighting the biological potential of benzocaine and its analogues shall open-up new dimensions of future research to design more potent analogues. PMID: 31518221 [PubMed - as supplied by publisher]
Source: Mini Reviews in Medicinal Chemistry - Category: Chemistry Authors: Tags: Mini Rev Med Chem Source Type: research