Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta ‐Analysis of 19 005 Individuals

ConclusionTwo NLRP3 ‐related SNPs showed potential interaction with SFA to modulate fasting insulin. Greater dietary SFA intake accentuates T2D risk, which, subject to functional validation, may be further elaborated depending on NLRP3‐related genetic variants.

Source: Molecular Nutrition and Food Research - September 11, 2019 Category: Food Science Authors: Aoife M. Murphy, Caren E. Smith, Leanne M. Murphy, Jack L. Follis, Toshiko Tanaka, Kris Richardson, Raymond Noordam, Rozenn N. Lemaitre, Mika K ähönen, Josée Dupuis, Trudy Voortman, Eirini Marouli, Dennis O. Mook‐Kanamori, Olli T. Raitak Tags: Research Article Source Type: research