The axis of local cardiac endogenous Klotho-TGF- β1-Wnt signaling mediates cardiac fibrosis in human

This study aimed to further clarify endogenous Klotho's functional roles in cardiac fibrosis in patients with underlying CKD.

Source: Journal of Molecular and Cellular Cardiology - September 10, 2019 Category: Cytology Authors: Qinghua Liu, Lang-Jing Zhu, Ana Maria Waaga-Gasser, Yan Ding, Minghua Cao, Shreyas J. Jadhav, Sandra Kirollos, Prem S. Shekar, Robert F. Padera, Yu-Chun Chang, Xingbo Xu, Elisabeth M. Zeisberg, David M. Charytan, Li-Li Hsiao Source Type: research