EP3 receptor is a prognostic factor in TA-MUC1-negative ovarian cancer.

CONCLUSION: The potential prognostic relevance of EP3 expression for OS in TA-MUC1 negative patients might reflect an interplay between the COX and the MUC1 pathway, as it has been shown that MUC1 could induce COX2 expression. Our findings support the importance of the prostanoid signaling in TA-MUC1 negative ovarian cancer; however, future studies are necessary to characterize specific pathways and possible interactions. PMID: 31485769 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31485769?dopt=Abstract

Source: Clin Med Res - September 3, 2019 Category: Research Authors: Czogalla B, Kuhn C, Heublein S, Schmöckel E, Mayr D, Kolben T, Trillsch F, Burges A, Mahner S, Jeschke U, Hester A Tags: J Cancer Res Clin Oncol Source Type: research