A phase II randomized clinical trial of the effect of metformin versus placebo on progression-free survival in women with metastatic breast cancer receiving standard chemotherapy.

CONCLUSION: In this population metformin showed no significant effect on RR, PFS or OS. These results do not support the use of metformin with chemotherapy in non-diabetic MBC patients. PMID: 31472446 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31472446?dopt=Abstract

Source: Breast - August 21, 2019 Category: Cancer & Oncology Authors: Pimentel I, Lohmann AE, Ennis M, Dowling RJO, Cescon D, Elser C, Potvin KR, Haq R, Hamm C, Chang MC, Stambolic V, Goodwin PJ Tags: Breast Source Type: research