Mesenchymal stem cell-derived extracellular vesicles improve the molecular phenotype of isolated rat lungs during ischemia/reperfusion injury

Lung ischemia/reperfusion (IR) injury contributes to development of severe complications in patients undergoing transplantation. Mesenchymal-stem-cells (MSCs)-derived Extracellular vesicles (EVs) exert beneficial actions comparable to those of MSCs without the risks of the cell-based strategy. The present research investigated EV-effects during IR injury in isolated rat lungs.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Pre-Clinical Science Source Type: research