Inhibition of TRPA1 and IL-6 signal alleviates neuropathic pain following chemotherapeutic bortezomib.
In conclusion, we revealed specific signaling pathways leading to neuropathic pain induced by chemotherapeutic BTZ, including IL-6-TRPA1, suggesting that blocking these signals is beneficial to alleviate neuropathic pain during BTZ intervention.
PMID: 31424261 [PubMed - as supplied by publisher]
Source: Physiological Research - Category: Physiology Authors: Liu D, Sun M, Xu D, Ma X, Gao D, Yu H Tags: Physiol Res Source Type: research
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