Inhibition of TRPA1 and IL-6 signal alleviates neuropathic pain following chemotherapeutic bortezomib.

In conclusion, we revealed specific signaling pathways leading to neuropathic pain induced by chemotherapeutic BTZ, including IL-6-TRPA1, suggesting that blocking these signals is beneficial to alleviate neuropathic pain during BTZ intervention. PMID: 31424261 [PubMed - as supplied by publisher]
Source: Physiological Research - Category: Physiology Authors: Tags: Physiol Res Source Type: research