Electrical stimulation mapping of language with stereo-EEG.

Electrical stimulation mapping of language with stereo-EEG. Epilepsy Behav. 2019 Aug 15;99:106395 Authors: Arya R, Ervin B, Dudley J, Buroker J, Rozhkov L, Scholle C, Horn PS, Vannest J, Byars AW, Leach JL, Mangano FT, Greiner HM, Holland KD, Glauser TA Abstract OBJECTIVE: We prospectively validated stereo-electroencephalography (EEG) electrical stimulation mapping (ESM) of language against a reference standard of meta-analytic functional magnetic resonance imaging (fMRI) framework (Neurosynth). METHODS: Language ESM was performed using 50 Hz, biphasic, bipolar, stimulation at 1-8 mA, with a picture naming task. Electrode contacts (ECs) were scored as ESM+ if ESM interfered with speech/language function. For each patient, presurgical MRI was transformed to a standard space and coregistered with computed tomographic (CT) scan to obtain EC locations. After whole-brain parcellation, this fused image data were intersected with three-dimensional language fMRI (Neurosynth), and each EC was classified as lying within/outside the fMRI language parcel. Diagnostic odds ratio (DOR) and other indices were estimated. Current thresholds for language inhibition and after-discharges (ADs) were analyzed using multivariable linear mixed models. RESULTS: In 10 patients (5 females), aged 5.4-21.2 years, speech/language inhibition was noted with ESM on 87/304 (29%) ECs. Stereo-EEG language ESM was a valid classifier of fMRI (Neurosynth) language sites (DOR: 9...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research

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Summary: Identifying the localization, distribution, and polarity of waveforms are the prime goals of clinical scalp EEG analysis. Appropriate choices of bipolar and referential montages are keys to emphasizing the diagnostic features of interest, and demand some understanding of the spatiotemporal physical behavior of the underlying neuronal generators. Several examples drawn from canonical epilepsy syndromes are used to illustrate this general message.
Source: Journal of Clinical Neurophysiology - Category: Neurology Tags: Invited Review Source Type: research
ConclusionOptimized SEEG-guided RF-TC is a promising complementary option for the treatment of MTLE-HS.
Source: Seizure - Category: Neurology Source Type: research
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Source: Techniques in Orthopaedics - Category: Orthopaedics Tags: Symposium Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens Family Inside Schizophrenia Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Mental Disorder Mental illness and Source Type: blogs
  Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens Family General Inside Schizophrenia Mental Health and Wellness Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Source Type: blogs
Conclusion: Multiple discrete sources have the power to transform the EEG back into the brain by defining new EEG traces in source space. Using standard source space 25, these can serve for improved clinical interpretation of EEG.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Publication date: October 2019Source: Epilepsy &Behavior, Volume 99Author(s): Ravindra Arya, Brian Ervin, Jonathan Dudley, Jason Buroker, Leonid Rozhkov, Craig Scholle, Paul S. Horn, Jennifer Vannest, Anna W. Byars, James L. Leach, Francesco T. Mangano, Hansel M. Greiner, Katherine D. Holland, Tracy A. GlauserAbstractObjectiveWe prospectively validated stereo-electroencephalography (EEG) electrical stimulation mapping (ESM) of language against a reference standard of meta-analytic functional magnetic resonance imaging (fMRI) framework (Neurosynth).MethodsLanguage ESM was performed using 50 Hz, biphasic, bipolar, stim...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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Source: BioImpacts - Category: Research Tags: Bioimpacts Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Disorders Inside Schizophrenia Psychiatry Source Type: blogs
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Source: Brain Stimulation - Category: Neurology Source Type: research
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