BLAST paradigm: A new test to assess brief attentional fluctuations in children with epilepsy, ADHD, and normally developing children

ConclusionsThis study demonstrates that attentional stability is impaired in children with epilepsy and/or ADHD. Bron–Lyon Attention Stability Test seems to be a sensitive test to detect attentional stability deficit in children with epilepsy and with attentional complaints who did not meet all criteria of ADHD.We propose that BLAST could be a useful clinical neuropsychological tool to assess attentional disorders in children.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

Related Links:

AbstractThe lack of cerebral creatine (Cr) causes intellectual disability and epilepsy. In addition, a significant portion of individuals with Cr transporter (Crt) deficiency (CTD), the leading cause of cerebral Cr deficiency syndromes (CCDS), are diagnosed with attention-deficit hyperactivity disorder. While the neurological effects of CTD are clear, the mechanisms that underlie these deficits are unknown. Part of this is due to the heterogenous nature of the brain and the unique metabolic demands of specific neuronal systems. Of particular interest related to Cr physiology are dopaminergic neurons, as many CCDS patients ...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
In conclusion, VPA administration during pregnancy results in malformations and attention-deficit/hyperactivity disorder-like behavioral abnormalities in the offspring. An increase in cell proliferation in the hippocampus may underlie the behavioral changes observed. Repeated use of high doses of VPA during pregnancy may increase the risk of neurodevelopmental abnormalities dose dependently and should be carefully considered. PMID: 31446017 [PubMed - as supplied by publisher]
Source: Brain Research - Category: Neurology Authors: Tags: Brain Res Source Type: research
CONCLUSIONS: This study demonstrates that attentional stability is impaired in children with epilepsy and/or ADHD. Bron-Lyon Attention Stability Test seems to be a sensitive test to detect attentional stability deficit in children with epilepsy and with attentional complaints who did not meet all criteria of ADHD. We propose that BLAST could be a useful clinical neuropsychological tool to assess attentional disorders in children. PMID: 31430660 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Publication date: Available online 10 August 2019Source: SeizureAuthor(s): Colin Reilly, Patricia Atkinson, Ayesha Memon, Chloe Jones, Lyvia Dabydeen, J. Helen Cross, Krishna B. Das, Christopher Gillberg, Brian G.R. Neville, Rod C. ScottAbstractPurposeTo provide data on the prevalence of Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), and parent reported behaviour difficulties in young children with epilepsy, and to compare results with children with neurodisability (neurodevelopmental/neurological difficulties) without epilepsy.MethodChildren with epilepsy (1-7 years, n = 48)...
Source: Seizure - Category: Neurology Source Type: research
(Natural News) Experts say there are over 600 disorders of the nervous system. These include epilepsy, brain tumors, cerebral palsy, attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASD), among others. Many of these emerge during childhood, and some can be diagnosed at birth. Oriental herbal medicine has been widely used in treating neurological disorders...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Publication date: Available online 5 August 2019Source: The Lancet PsychiatryAuthor(s): Janneke R Zinkstok, Erik Boot, Anne S Bassett, Noboru Hiroi, Nancy J Butcher, Claudia Vingerhoets, Jacob A S Vorstman, Therese A M J van AmelsvoortSummary22q11.2 deletion syndrome is characterised by a well defined microdeletion that is associated with a high risk of neuropsychiatric disorders, including intellectual disability, schizophrenia, attention-deficit hyperactivity disorder, autism spectrum disorder, anxiety disorders, seizures and epilepsy, and early-onset Parkinson's disease. Preclinical and clinical data reveal substantial ...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Behavioral comorbidity is the rule rather than the exception in autism spectrum disorder (ASD), and the co-occurrence of autistic traits with subclinical manifestations of other psychiatric syndromes (e.g. anxiety, developmental coordination disorder) extends to the general population, where there is strong evidence for overlap in the respective genetic causes. An ASD “comorbidity” can have several fundamentally-distinct causal origins: it can arise due to shared genetic risk between ASD and non-ASD phenotypes (e.g., ASD and microcephaly in the context of the MECP2 mutation), as a “secondary symptom&rdquo...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: In Context Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Clinical NeuroscienceAuthor(s): Zeynep Selen Karalok, Zeynep Öztürk, Altan GunesAbstractThe aim of this study is to evaluate the abnormal cortical structures associated with newly diagnosed benign epilepsy with centrotemporal spikes (BECTS) patients and assessed the effects of comorbid attention-deficit/hyperactivity (ADHD) on these abnormalities. Newly diagnosed BECTS patients (n = 33, 23 males) and age-matched healthy controls (n = 48) were evaluated by surface and volumetric MRI. CAT12 toolbox (HYPERLINK “http://www.neuro.uni-jena....
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 22 June 2019Source: Seminars in Cell &Developmental BiologyAuthor(s): Maude Bordeleau, Micaël Carrier, Giamal N. Luheshi, Marie-Ève TremblayAbstractIn addition to their traditional role as immune sentinels, recent discoveries over the last decade have shown that microglial functions now include regulation of neuronal/glial cell migration, differentiation and maturation, as well as neuronal network formation. It was thus proposed that disruption of these microglial roles, during critical periods of brain development, could lead to the pathological onset of several neurodeve...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
This article is part of the Special Issue "Epilepsy and social cognition across the lifespan"
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
More News: ADHD | Brain | Child Development | Children | Epilepsy | Hyperactivity | Men | Neurology | Statistics | Study