Chronic consumption of a high-fat diet rich in corn oil activates intrinsic cell death pathway and induces several ultrastructural changes in the atria of healthy and type 1 diabetic rat.

In conclusion, chronic consumption of CO-HFD by T1DM-induced rats elicits significant biochemical and ultrastructural damage to rat atrial cells accompanied by elevated oxidative stress and mitochondria-mediated cell death. This article is protected by copyright. All rights reserved.
PMID: 31398260 [PubMed - as supplied by publisher]

Source: Clinical and Experimental Pharmacology and Physiology - August 8, 2019 Category: Drugs & Pharmacology Authors: Eid RA, Eleawa SM, Alkhateeb MA, Aldera H, Zaki MSA, Al-Shraim M, Saeed MA, El-Kott AF, Alaa Eldeen M, Alassiri M, Alshehri MM, Salem Al-Shudiefat AA, Khalil MA Tags: Clin Exp Pharmacol Physiol Source Type: research