Cinnamaldehyde induces pumps expression and multidrug resistance in Pseudomonas aeruginosa.

In conclusion, use of cinnamon bark oil or cinnamaldehyde as adjunctive therapy to treat P. aeruginosa infections may potentially have antagonistic effects if combined with antibiotics because of Mex pumps activation.
PMID: 31383658 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - August 4, 2019 Category: Microbiology Authors: Tétard A, Zedet A, Girard C, Plésiat P, Llanes C Tags: Antimicrob Agents Chemother Source Type: research