Maine Confirmed Its First Case of a Rare Tick-Borne Virus in Years. Here ’s What to Know About Powassan

Health officials have confirmed that an individual in Maine is sick with Powassan virus disease, marking the first time since 2017 that a person in the state has come down with the rare and serious tick-borne illness. The Maine Center for Disease Control and Prevention announced Wednesday that a southern Maine resident was hospitalized for Powassan encephalitis—brain inflammation associated with the virus—after showing symptoms in late June. The announcement did not specify the individual’s current condition, but health officils doctors to stay vigilant about the potential spread of Powassan throughout the summer and early fall. Here’s what to know about the tick-borne Powassan virus disease. What is Powassan virus disease? Like Lyme disease, Powassan is spread by the bite of an infected tick, which typically picks up the virus after feeding on animals carrying it in their blood. Powassan, however, is far rarer than Lyme disease in the U.S. There were 21 reported cases nationwide last year, and the 33 reported cases in 2017 marked the most the U.S. has seen in the past decade, according to U.S. Centers for Disease Control and Prevention (CDC) data. Since 2009, most cases have been reported in New England and the Great Lakes region, with the highest count in Minnesota. Powassan virus disease is typically spread by the deer tick (scientifically known as Ixodes scapularis) or the groundhog tick (Ixodes cookei), according to the CDC. What are the symptom...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Maine onetime Source Type: news

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Publication date: 2019Source: Advances in Virus Research, Volume 104Author(s): Eva Mittler, Maria Eugenia Dieterle, Lara M. Kleinfelter, Megan M. Slough, Kartik Chandran, Rohit K. JangraAbstractHantaviruses are important zoonotic pathogens of public health importance that are found on all continents except Antarctica and are associated with hemorrhagic fever with renal syndrome (HFRS) in the Old World and hantavirus pulmonary syndrome (HPS) in the New World. Despite the significant disease burden they cause, no FDA-approved specific therapeutics or vaccines exist against these lethal viruses. The lack of available interven...
Source: Advances in Virus Research - Category: Virology Source Type: research
Publication date: 2019Source: Advances in Virus Research, Volume 104Author(s): Mitsuhiro Nishimura, Yasuko MoriAbstractIn this chapter, we present an overview on betaherpesvirus entry, with a focus on human cytomegalovirus, human herpesvirus 6A and human herpesvirus 6B. Human cytomegalovirus (HCMV) is a complex human pathogen with a genome of 235 kb encoding more than 200 genes. It infects a broad range of cell types by switching its viral ligand on the virion, using the trimer gH/gL/gO for infection of fibroblasts and the pentamer gH/gL/UL128/UL130/UL131 for infection of other cells such as epithelial and endothelial...
Source: Advances in Virus Research - Category: Virology Source Type: research
Publication date: Available online 19 August 2019Source: Veterinary MicrobiologyAuthor(s): Jéssica Caroline Gomes Noll, Lok Raj Joshi, Gabriela Mansano do Nascimento, Maureen Hoch Vieira Fernandes, Bishwas Sharma, Eduardo Furtado Flores, Diego Gustavo DielAbstractCaprine alphaherpesvirus 1 (CpHV-1) is a pathogen associated with systemic infection and respiratory disease in kids and subclinical infection or reproductive failure and abortions in adult goats. The enzyme thymidine kinase (TK) is an important viral product involved in nucleotide synthesis necessary for virus replication. Therefore, it is a common target ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
This study assessed different dust collection methods for MDV and ILTV detection in a vaccinated layer flock (n = 1700) from day-old to 50 weeks of age. Birds were vaccinated against MDV at day-old, and ILTV by drinking water at week 6 and eye drop at week 12. Dust samples were collected weekly by settle plates (13 plates/15 m2) or by scraping surfaces in the poultry shed and tested for ILTV and MDV genomic copies (GC) by PCR. ILTV GC were detected 4 weeks post water vaccination, peaked at weeks 1214 and became mostly undetectable after week 18. MDV was detected in dust on week 1, peaked at weeks 3-6, decline...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
ConclusionWe demonstrated that immune responses induced by FAGP reduced the growth, development, and reproduction of A. cantonensis in subsequent infections. While the possibility of using FAGP combining with MA or FA antigens as a multi-function vaccine in immune protection against A. cantonensis needs to be further elucidated, we hope that it provides a novel strategy for this parasite vaccine development.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
Publication date: Available online 19 August 2019Source: Journal of Theoretical BiologyAuthor(s): Yuting Wei, Yaosen Lin, Bin WuAbstractVaccination is crucial for the control of epidemics. Yet it is a social dilemma since non-vaccinators benefit from the herd immunity created by the vaccinators. Thus the optimum vaccination level is not reached via voluntary vaccination at times. Social networks have been shown to dramatically alter the vaccination behavior. The underlying network, however, is often assumed to be static, neglecting the dynamical nature of social networks. We address how the dynamics of networks have an imp...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
In conclusion, the expression pattern of genes related to the humoral and cell-mediated adaptive immune response showed upregulation in fish infected with P. salmonis and down-regulation in vaccinated fish. The results of this study contribute to our understanding of the immune response against P. salmonis and can be used in the optimization of SRS prevention and control measures.
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
(CNN) — Health officials in Maine are warning about the potential for more cases of Powassan virus disease after one person was confirmed to be sick with the rare tick-borne illness, the first reported case in the state since 2017. The Maine Center for Disease Control and Prevention said Wednesday that a person in the southern part of the state had Powassan encephalitis, a severe disease that causes inflammation in the brain. The agency said the patient showed symptoms in late June and was hospitalized. The Maine CDC issued an advisory to physicians that more cases could be possible and suggested that doctors conside...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health CNN Maine news powassan virus ticks Source Type: news
Abstract Tick-borne encephalitis (TBE) is an arbovirus induced by tick-borne encephalitis virus (TBEV) transmitted by tick bite. The disease is rare in France (two to three cases per year) but endemic zones extend from Western Europe to the east coast of Asia (10,000-15,000 cases per year). An 8-year-old boy was admitted to our pediatric ward in Strasbourg (France) for febrile headache with diplopia. Four days after a tick bite, he declared a febrile headache together with maculopapular rash on the elbows, knees, and cheeks. Fourteen days after the outbreak of symptoms, he showed confusion, drowsiness, and binocul...
Source: Archives de Pediatrie - Category: Pediatrics Authors: Tags: Arch Pediatr Source Type: research
Discussion Arboviruses are viruses transmitted by arthropods (primarily mosquitos and ticks) to humans. Most infections are asymptomatic. Many others have mild symptoms such as an influenza-like illnesses. But for some patients they can cause neuroinvasive disease with meningitis, encephalitis and flaccid paralysis. Some patients also unfortunately die. Diagnosis is by serum or cerebrospinal fluid IgM antibody to the specific virus. Treatment is supportive only as there is no specific treatment and currently there are no vaccines for prevention. Mosquito bite and tick bite prevention are the best options for families and c...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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