Systemic and environmental risk factors for recurrent aphthous stomatitis in a Polish cohort of patients.

Systemic and environmental risk factors for recurrent aphthous stomatitis in a Polish cohort of patients. Postepy Dermatol Alergol. 2019 Apr;36(2):196-201 Authors: Ślebioda Z, Dorocka-Bobkowska B Abstract Introduction: Recurrent aphthous stomatitis (RAS) is a common oral mucosal disease without a clearly defined etiology. Aim: To analyze the influence of systemic diseases, medications, smoking and a family history of RAS on the prevalence and the course of the condition in Polish patients with RAS. Material and methods: Seventy-eight patients with RAS and 72 subjects without a history of RAS were enrolled in the study. All participants underwent a detailed oral examination and a full blood count. The results were statistically analyzed with Statistica 10 (StatSoft, Krakow, Poland) with Mann-Whitney, Kruskal-Wallis, χ2 and Fisher tests, with p
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

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In conclusion, this study provides a systematic analysis of the expression of TRAIL-Rs in human primary B cells and of their capacity to signal and induce apoptosis. This dataset forms a basis to further study and understand the dysregulation of TRAIL-Rs and TRAIL expression observed in autoimmune diseases. Additionally, it will be important to foresee potential bystander immunomodulation when TRAIL-R agonists are used in cancer treatment. Introduction The homeostasis of humoral immunity requires a tight control of generation, survival, activation and maturation of B lymphocytes. Therefore, pro-survival and pro-apo...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
The patient is a 3 year old female with tricho-hepato-enteric syndrome (THE-S) admitted for an Escherichia-coli central line associated bloodstream infection. Medical history includes chronic diarrhea (baseline 4-5 loose stools per day) with total parenteral nutrition (TPN) via central line, failure to thrive (FTT), reno-vascular hypertension, iron deficiency anemia, liver impairment, multiple line infections, and pneumonia. She was born via cesarean section at 35 weeks estimated gestational age (EGA) due to intrauterine growth restriction (IUGR).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
A 3-year-old girl with trichohepatoenteric syndrome (THE-S) was admitted for an Escherichia coli central catheter –associated bloodstream infection. Her medical history includes chronic diarrhea (baseline of 4-5 loose stools per day) with total parenteral nutrition (TPN) via central catheter, failure to thrive (FTT), renovascular hypertension, iron deficiency anemia, liver impairment, multiple catheter infect ions, and pneumonia. She was born via cesarean section at an estimated gestational age of 35 weeks because of intrauterine growth restriction.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Conclusion The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1. The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - Category: International Medicine & Public Health Authors: Source Type: research
Follow me on Twitter @RobShmerling Ever wonder what other people are wondering about? I know I do. So, here are the top 10 health searches in Google for 2017. And just so you don’t have to look each one up, I’ve provided a brief answer. You’re welcome. 1.  What causes hiccups? I was surprised this one made it to the top 10 list of health searches. Maybe this search is common because hiccups are as mysterious as they are universal. I’ve written about hiccups before, but let’s just say the cause in any individual person is rarely known or knowable. Then again, the reason hiccups stop is als...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Source Type: blogs
A 73-year-old woman with a history of atrial fibrillation status post ablation who was receiving anticoagulation with warfarin presented to the general internal medicine clinic without symptoms or concerns for an annual physical examination. Her medical history included hypertension, hyperlipidemia with statin intolerance, osteopenia, osteoarthritis, impaired fasting glucose levels, fibrocystic breast changes, seasonal allergies, and a thyrocervical trunk aneurysm that was stable on serial ultrasonographic imaging.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Residents' clinic Source Type: research
If you're one of the more than 20 million Americans who suffer from chronic kidney disease (CKD), your doctor has probably told you there isn't much they can do for you. Mainstream medicine doesn't have a cure for CKD. What they do have is a lot of drugs to treat the symptoms of it. And most of the drugs will leave you worse off than before you started taking them… Like ESAs, which are prescribed to treat anemia caused by chronic kidney disease. These dangerous drugs can cause strokes, heart attacks, blood clots and seizures. And if your kidneys fail, your only options are dialysis or a kidney transplant...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
By Brandon R. Peters, MD When sleep is not refreshing, the feelings of tiredness and fatigue can undermine your daytime function. Beyond common sleep disorders like obstructive sleep apnea and insomnia, what are some of the reasons for feeling tired? Explore some of these potential causes, ranging from medications to diet and exercise, and try to discover what you can do to feel better. Understanding the Role of Sleep Disorders First, it is important to recognize that there is a difference between sleepiness and fatigue. Sleepiness is the strong desire for sleep that often immediately precedes falling asleep. It is some...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
AMSTERDAM – Five people with confirmed Zika virus infections have died in Colombia, and all had medical comorbidities, including leukemia, diabetes, sickle cell anemia, and hypertension. All of the deaths occurred last October in northern and central Colombia, Dr. Alfonso Rodriguez-Morales said at...
Source: Skin and Allergy News - Category: Dermatology Source Type: news
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