Effect of palmitate and oleate on mitochondrial dynamics processes in hepatic cells HEPG2

Introduction: Mitochondria are organelles constantly submitted to fusion and fission processes (mitochondrial dynamics). Fission process is associated with mitochondrial disfunction, oxidative stress and apoptosis, and therefore with insulin resistance onset. On the other hand, fusion process is associated with the prevention of this metabolic alteration, being able to protect cells against insulin resistance.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Isy Faria de Sousa, Marilena Lepretti, Vincenzo Migliaccio, Gaetana Paolella, Eliane Beraldi Ribeiro, Lill à Lionetti Source Type: research