Food database of endocannabinoids, N-acylethanolamines and N-acylphosphatidylethanolamines and daily intake in Western, Mediterranean and Vegetarian diets

Introduction: N-acylphosphatidylethanolamines (NAPEs), N-acylethanolamines (NAEs), and the endocannabinoids (ECs) are lipids involved in different physiological processes in both animals and plants. NAEs derive from NAPEs through the action of NAPE-PLD. NAEs can be hydrolyzed by FAAH and form free fatty acids and ethanolamine. In animals, NAEs and ECs activate the cannabinoids receptors, the vanilloid receptor/TRPV1, peroxisome proliferator-activated receptor- α (PPAR-α) and G protein-coupled receptors present along the gastrointestinal tract (GIT).

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Lucia De Luca, Paola Vitaglione Source Type: research