Validating Reward-related Biomarkers (RTOC)

Conditions:   Schizophrenia;   Depression;   Motivation;   Anhedonia, Physical;   Anhedonia, Social;   Negative Symptoms With Primary Psychotic Disorder Interventions:   Behavioral: Self-rating Questionnaires;   Behavioral: Measures of Reward processing/reinforcement learning;   Behavioral: Additional Schizophrenia-specific Questionnaires and Interviews Sponsors:   Maastricht University;   P1vital Products LTD.;   BIOTRIAL;   University Hospital Frankfurt, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy;   The Institute of Neuropsychiatry and Addictions (INAD), Parc de Salut Mar, Barcelona;   Aristotle University of Thessaloniki, School of Medicine, Department of Clinical Pharmacology;   Maastricht University, School for Mental Health and Neuroscience Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Today’s guest is Okpara Rice, CEO of Tanager Place, a mental health facility for children in Cedar Rapids, Iowa.  Unlike adults, children are not in control of their own environment, and anything that affects a child will affect their families, and vice versa.  So, what is the best way to help these kids?  Join us as Okpara and Gabe talk about the importance of a holistic approach to mental illness in children, approaches which may or may not include medication. SUBSCRIBE &REVIEW   Guest information for ‘Children’s Mental Health’ Podcast Episode Okpara Rice joined Tanager...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens Mental Health and Wellness Relationships The Psych Central Show Treatment Source Type: blogs
Police officers are often the first responders when someone is having a mental illness crisis.  But are members of law enforcement properly equipped for this job?  There are plenty of horrifying stories that would indicate that the answer is “no.”  How do we change this?  Join us as Gabe speaks with Officer Rebecca Skillern from the Huston, Texas, Police Department about how Houston is training its officers to respond to these difficult calls. SUBSCRIBE &REVIEW   Guest information for ‘Policing and Crisis Intervention Training’ Podcast Episode   Officer Rebecca S...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Policy and Advocacy Relationships The Psych Central Show Source Type: blogs
Conditions:   Schizophrenia;   Depression;   Motivation;   Anhedonia, Physical;   Anhedonia, Social;   Negative Symptoms With Primary Psychotic Disorder Interventions:   Behavioral: Self-rating Questionnaires;   Behavioral: Measures of Reward processing/reinforcement learning;   Behavioral: Additional Schizophrenia-specific Questionnaires and Interviews Sponsors:   Maastricht University;   P1vital Products LTD.;   BIOTRIAL;   University Hospital Frankfurt, Department of Psychiatry, Psychosomatic Medi...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
 Jennifer Marshall is a mom, executive director, storyteller, and a woman living with bipolar disorder. In 2011, she started chronicling her challenges of living with mental illness while raising two young children.  Her story was a powerful one and connected with people all over the country, many of whom wrote to her to say that they had been inspired after reading her blog.  Jennifer knew she was onto something, and that storytelling was a powerful tool for healing.  This was the beginning of ‘This Is My Brave’ – a nonprofit with the mission of bringing stories of mental illness and ad...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Relationships Self-Help The Psych Central Show Women's Issues Source Type: blogs
Conclusion: This is the first implementation of SocialMind, which is the first mindfulness-based social cognition training. It is well tolerated by participants with schizophrenia spectrum disorders, and a further randomized controlled trial is proposed for people who have suffered their first episode of psychosis within the past 5 years.Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT03434405.IntroductionPeople suffering from psychosis frequently find it difficult to establish or maintain relationships with others or to engage in community activities (1, 2). These deficits are present even in high-risk ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ConclusionThe research project aims to directly improve identification and support of vulnerable children across selected regions in Austria, and by doing so, improve the health and well-being of future Austrian generations while breaking the cycle of intergenerational transfer of adverse childhood experiences. The described project underwent a rigorous public review process (https://ois.lbg.ac.at/en/methods-projects/crowdsourcing-research-questions-in-science) with different stakeholders as well as people with lived experience and scientific experts of the field having reviewed our proposal (https://ois.lbg.ac.at/en/metho...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: CBT, psychosocial intervention, supportive counseling, psychodynamic psychotherapy, and other psychological interventions can be recommended for clinical practice. More studies are needed, especially for non-CBT interventions and for all psychotherapies on negative symptoms.IntroductionSchizophrenia affects approximately 1% of the population, usually starting in adolescence or young adulthood, frequently leading to persistent disability, with a high risk of suicide (8%). Despite the advance in antipsychotics treatment, approximately 30% of patients with schizophrenia show a poor response or no response to anti...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion Currently available pharmacotherapies for PTSD are poorly effective on a substantial proportion of patients. Given this high rate of pharmacological unresponsiveness, further studies are needed to extend the knowledge of the basic mechanisms associated with the pathophysiology of this disorder. The findings discussed in this review suggest that DAergic dysfunction, especially genetic-dependent DAergic alteration, plays a prominent role in the pathophysiology of PTSD; as a consequence, drugs targeting the DAergic system might be therapeutically relevant. A better understanding of how and which DAergic dysfunctio...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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