SmartTots 2013 Request for Applications

SmartTots 2013 Request for Applications SmartTots is now accepting applications aimed at investigating whether anesthetics/sedatives are neurotoxic and/or impede the normal development of the human brain. Up to two projects will be selected to receive a maximum of $200,000 each. Project Guidelines: • Projects should focus on whether neonatal anesthetic exposure in humans impairs brain development resulting in persistent detrimental effects on cognition or behavior. Studies aimed at identifying either specific anesthetic techniques that do not produce neurotoxic effects or interventions to ameliorate damage will also be considered. Retrospective or prospective studies in any species will be considered, provided they inform the existence of anesthetic-induced developmental neurotoxicity in humans. • Specific questions of interest include: ■ Do short and/or long anesthetic exposures in human neonates result in neuronal or glial cell death, or structural and/or functional abnormalities of the brain? ■ Do short and/or long anesthetic exposures in human neonates result in persistent behavioral abnormalities (intellectual, motor, social, emotional, etc)? ■ Are anesthetics and/or sedatives of specific frequency, duration, or timing of exposure correlated with detrimental effects on brain structure or function in humans? • Funds should be used only for research support and direct costs; institutional indirect expenses will not be fu...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding