Polymorphism in Organic Anion-Transporting Polypeptide Gene Related to Methotrexate Response in Rheumatoid Arthritis Treatment.

CONCLUSIONS: The rs11045879 minor allele in the SLCO1B1 gene is a potential predictor of non-responders to MTX treatment among Japanese RA patients. In future collaborative research, we will investigate whether the association with SLCO1B1 polymorphism is significant by performing statistical analysis with a larger study population.
PMID: 31292326 [PubMed - in process]

Source: Journal of Nippon Medical School - July 13, 2019 Category: Universities & Medical Training Authors: Takahashi K, Nakamura H, Watanabe A, Majima T, Koiwa M, Kamada T, Takai S Tags: J Nippon Med Sch Source Type: research