Enzyme responsible for dangerous properties of brain tumor stem cells

(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) The relapse of brain tumors after therapy is driven by cancer stem cells that were not affected by the treatment. In mouse models of glioblastoma, scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) were now looking for molecular markers that specifically characterize brain tumor stem cells. They identified an enzyme that is responsible for the threatening stem cell properties of glioblastoma and at the same time represents a possible 'Achilles heel' where cancer stem cells could be vulnerable.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news