Efficacy of antiepileptic drugs in the era of pharmacogenomics: A focus on childhood.

CONCLUSION: Variability in genes coding for sodium channels, drug transporters and cytochrome P450 enzymes can have a significant impact on response to antiepileptic drugs. Larger prospective studies with better stratification of samples are needed to shed light on these associations.
PMID: 31280948 [PubMed - as supplied by publisher]

Source: European Journal of Paediatric Neurology - June 27, 2019 Category: Neurology Authors: Gogou M, Pavlou E Tags: Eur J Paediatr Neurol Source Type: research