QKI deficiency maintains glioma stem cell stemness by activating the SHH/GLI1 signaling pathway

ConclusionOur data indicate that upregulation of GLI1 induced by QKI deficiency maintains GSC stemness and enhances the invasiveness of GBM cells, thereby hinting at new options for the treatment of GBM.

Source: Cellular Oncology - July 9, 2019 Category: Cancer & Oncology Source Type: research