Ketones improves Apolipoprotein E4-related memory deficiency via sirtuin 3.

CONCLUSION: Our current studies suggest that ketones improve learning and memory abilities of ApoE4 transgenic mice. Sirt3 may mediate the neuroprotection of ketones by increasing neuronal energy metabolism in ApoE4 transgenic mice. This provides the foundation for Sirt3's potential role in the prevention and treatment of AD. PMID: 31280254 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31280254?dopt=Abstract

Source: Aging - July 6, 2019 Category: Biomedical Science Authors: Yin J, Nielsen M, Li S, Shi J Tags: Aging (Albany NY) Source Type: research