Low Free Sugar Diet in Adolescents With Nonalcoholic Fatty Liver Disease —Reply

In Reply Messrs Tang and Gao raise 2 questions regarding our study of dietary sugar in pediatric nonalcoholic fatty liver disease. They suggest that the effect observed in our trial may have been solely a function of weight loss. The study was not designed to promote weight loss; participants ate without calorie or macronutrient restriction. In support of the argument for a weight loss effect, Tang and Gao reference practice guidelines that were written primarily for adults with nonalcoholic fatty liver disease and recommend weight loss of 5% to 10% of body weight.
Source: JAMA - Category: General Medicine Source Type: research