Noninvasive Seizure Localization With Single-Photon Emission Computed Tomography Is Impacted by Preictal/Early Ictal Network Dynamics

Conclusion: Slowly evolving seizures are more likely to be accurately imaged with SPECT, and the identified focus may overlap with brain regions where significant t- pological changes occur. Significance: Measures of preictal/early ictal network dynamics may help optimize the SPECT localization, leading to improved surgical and neurostimulation outcomes in refractory epilepsy.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research