Introduction and classical environmental risk factors for Parkinson.

Introduction and classical environmental risk factors for Parkinson. Rev Neurol (Paris). 2019 Jun 18;: Authors: Tranchant C Abstract Several environmental toxics are known to induce or to increase occurrence of Parkinson disease while other toxics can provoke basal ganglia necrosis and dopa resistant parkinsonism. After this introduction, the relationship between environment and parkinsonism will be illustrated by 3 short papers: interaction gene-environment, manganese induced Parkinsonism and the Caribbean Food toxins Parkinson plus syndromes. PMID: 31227125 [PubMed - as supplied by publisher]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: It seems possible to identify a morphologic intestinal disease substrate in Parkinson's disease by H&E staining, showing ganglion cell pycnosis and degeneration in both plexa. This finding may indicate a potential to diagnose enteric neuropathy in highly accessible sites. PMID: 31321021 [PubMed]
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
This study explores the effectiveness of thymol blue for the first time together with supramolecular solvent to develop green supramolecular solvent liquid–phase microextraction method to preconcentrate and separate of trace amount of Aluminum (III) in real samples.Graphical abstractThe procedure of the supramolecular solvent liquid–phase microextraction technique.
Source: Microchemical Journal - Category: Chemistry Source Type: research
To determine whether non-motor symptoms predict the development of functional dependency in Parkinson's disease (PD).
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research
PARKINSON ’S DISEASE is a progressive disease of the nervous system marked by certain symptoms. There are six early symptoms to spot that could mean the disease is prevalent. What are they?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 19 July 2019Source: NeuroscienceAuthor(s): Valeria Belluscio, Samuel Stuart, Elena Bergamini, Giuseppe Vannozzi, Martina ManciniAbstractTurning elicits Freezing of Gait (FoG) episodes in people with Parkinson's disease (PD) and is thought to require higher cortical control compared to straight ahead gait. Functional near infrared spectroscopy (fNIRS) has been used to examine prefrontal cortex (PFC) activity while walking, but the relationship between PFC activity and turn performance remains unclear. The aim of this pilot study was to examine PFC activity during turning in PD and healthy ...
Source: Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 19 July 2019Source: NeuroImageAuthor(s): Osvaldo Matías Velarde, Eugenio Urdapilleta, Germán Mato, Damián DellavaleAbstractPhase-amplitude cross frequency coupling (PAC) is a rather ubiquitous phenomenon that has been observed in a variety of physical domains; however, the mechanisms underlying the emergence of PAC and its functional significance in the context of neural processes are open issues under debate.In this work we analytically demonstrate that PAC phenomenon naturally emerges in mean-field models of biologically plausible networks, as a signature of specifi...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: Available online 19 July 2019Source: Clinica Chimica ActaAuthor(s): Giulia Bivona, Bruna Lo Sasso, Giorgia Iacolino, Caterina Maria Gambino, Concetta Scazzone, Luisa Agnello, Marcello CiaccioAbstractThe current review provides an overview on the development of 25(OH)D measurement standardization tools over the last three decades and clarifies whether there is a role as a serum biomarker for vitamin D in neurological diseases. In the past, a lack of internationally recognized 25(OH)D reference measurement procedures and reference standard materials led to unstandardized serum total 25(OH)D results among re...
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AbstractMicrosatellite repeat expansion disease loci can exhibit pleiotropic clinical and biological effects depending on repeat length. Large expansions inC9orf72 (100s –1000s of units) are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). However, whether intermediate expansions also contribute to neurodegenerative disease is not well understood. Several studies have identified intermediate repeats in Par kinson’s disease patients, but the association was not found in autopsy-confirmed cases. We hypothesized that intermediateC9orf72 repeats are a genet...
Source: Acta Neuropathologica - Category: Neurology Source Type: research
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Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research
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