SIRT6, a novel direct transcriptional target of FoxO3a, mediates colon cancer therapy

Conclusion: The results uncover SIRT6 as a new potential biomarker for colon cancer, and its unappreciated mechanism about transcription and expression via Akt/FoxO3a pathway.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Yingjie Zhang, Liming Nie, Keqian Xu, Yang Fu, Juchang Zhong, Kongzhen Gu, Lingling Zhang Tags: Research Paper Source Type: research