Conversion of computational human phantoms into DICOM-RT for normal tissue dose assessment in radiotherapy patients.

Conversion of computational human phantoms into DICOM-RT for normal tissue dose assessment in radiotherapy patients. Phys Med Biol. 2019 Jun 03;: Authors: Griffin KT, Mille M, Pelletier C, Gopalakrishnan M, Jung JW, Lee C, Kalapurakal J, Pyakuryal A, Lee C Abstract Radiotherapy treatment planning systems are designed for the fast calculation of dose to the tumor bed and nearby organs at risk using x-ray computed tomography (CT) images. However, CT images for a patient are typically available for only a small portion of the body, and in some cases, such as for retrospective epidemiological studies, no images may be available at all. When dose to organs that lie out-of-scan must be estimated, a convenient alternative for the unknown patient anatomy is to use a matching whole-body computational phantom as a surrogate. The purpose of the current work is to connect such computational phantoms to commercial radiotherapy treatment planning systems for retrospective organ dose estimation. A custom software with graphical user interface, called the DICOM-RT Generator, was developed in MATLAB to convert voxel computational phantoms into the Digital Imaging and Communications in Medicine radiotherapy (DICOM-RT) format, compatible with commercial treatment planning systems. DICOM CT image sets for the phantoms are created via a density-to-Hounsfield unit conversion curve. Accompanying structure sets containing the organ contours are automaticall...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research