Independent and incremental value of Ventilation/Perfusion PET/CT and CT pulmonary angiography for pulmonary embolism diagnosis: results of the PECAN pilot study

Conclusions: In this pilot study, we have demonstrated the feasibility and potential utility of V/Q PET/CT for the management of patients with suspected acute PE. V/Q PET/CT may be of particular relevance in cases of equivocal findings or isolated subsegmental findings on CTPA, adding further discriminatory information to allow important decision-making regarding application or withholding of treatment courses of therapeutic anticoagulation, which may confer an increased risk of bleeding. Given the other advantages of V/Q PET/CT (reduced acquisition time, low radiation dose), and with increasing availability of 68Ga-generators, PET/CT is a potential replacement to V/Q SPECT/CT imaging.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Le Roux, P. Y., Iravani, A., Callahan, J., Burbury, K., Eu, P., Steinfort, D., Lau, E., Salaun, P., Hicks, R., Hofman, M. Tags: Outcomes/Infectious Disease/Pulmonary II Source Type: research