Editorial: The Promise of Psychiatric Translational Research: Exploring How the Gut Can Influence Brain Development

How the gastrointestinal (GI) tract can influence the development and functioning of the central nervous system is one of the hottest translational research topics today. In animal studies, GI infections have been linked to enteric inflammation, disrupted intestinal permeability, and changes in diversity in the gut microbiome as well as brain dysfunction.1 In humans, infectious gastroenteritis has been associated with modified composition of the gut microbiome and systemic inflammation.2 While gastroenteritis has not been causally linked to dysregulation of the brain in humans, it has been associated with later chronic GI conditions such as irritable bowel syndrome which is often accompanied by anxiety and depression.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Editorial Source Type: research