Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3.

CONCLUSION: Three hundred and forty-seven genes associated with autophagy in human pancreatic cancer were concentrated, and a key gene ubiquitin C which is closely related to the occurrence of PNI was determined, suggesting that LC3 may influence the PNI and prognosis of pancreatic cancer through ubiquitin C.
PMID: 31114135 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - May 6, 2019 Category: Gastroenterology Authors: Yang YH, Zhang YX, Gui Y, Liu JB, Sun JJ, Fan H Tags: World J Gastroenterol Source Type: research