Pediatric ovarian immature teratoma: Histological grading and clinical characteristics

Ovarian immature teratomas (ITs) are relatively rare among all pediatric ovarian tumors. The histological grading for ovarian ITs, which ranges from 1 to 3, is based on the proportion of immature neuroepithelial component. Higher-grade ITs in adults are treated as malignant neoplasms and require adjuvant chemotherapy. However, there is no consensus on the therapeutic management of pediatric ovarian ITs. The aim of our study was to analyze the histological grades and clinical characteristics of ovarian ITs in pediatric patients.

Source: Journal of Pediatric Surgery - May 22, 2019 Category: Surgery Authors: Toko Shinkai, Kouji Masumoto, Fumiko Chiba, Kazuki Shirane, Yasunari Tanaka, Tsubasa Aiyoshi, Takato Sasaki, Kentaro Ono, Chikashi Gotoh, Yasuhisa Urita, Hajime Takayasu, Ryoko Suzuki, Shingo Sakashita Source Type: research