Lipid peroxidation as a predictive biomarker of the early stage of cancer.

Lipid peroxidation as a predictive biomarker of the early stage of cancer. J Biol Regul Homeost Agents. 2019 May 16;33(3) Authors: Bobrowska-Korczak B, Skrajnowska D, Kiss AK, Wrzesien R, Bielecki W, Orzoł A, Zebrowski P, Bialek S Abstract Prostate cancer continues to be a major cause of morbidity and mortality in men around the world. The data concerning the antioxidant status and the degree of lipid peroxidation at the moment of the initiation of cancer is limited. The aim of this research is to assess the effect of selected minerals (zinc, selenium, iron, copper and calcium) on the growth of the neoplastic process and the concentrations of selected biomarkers of the oxidative damage in rats with implanted prostate cancer cells. It was found that the diet supplementation with selected minerals (zinc, selenium, iron, copper and calcium) affect the occurrence of prostate tumor growth in the examined rats. The intraperitoneal implantation of prostate cancer cells resulted in the occurrence of prostatic adenoma in 71% of the examined rats. In the rats that were additionally supplemented with selenium and with copper, the cancer cell aggregates constituted, respectively, 25% and 38% of the cases. As a result of implantation of cancer cells, the level of biomarkers of lipid peroxidation increased both in the urine and in tissues of the examined animals (rat group without supplementation). No relationship was found between the process of lipid peroxidation du...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

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ConclusionUndifferentiated pleomorphic sarcoma should be a differential in subcutaneous lesions in older adults with a previous history of malignancy, radiation therapy and a mass in the subcutaneous tissue of the back.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conditions:   MRI Guided Transurethral Ultrasound Ablation;   Localized Prostate Cancer;   Ablation Therapy Intervention:   Procedure: Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Tissue Sponsor:   University Hospital, Strasbourg, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Prostate Cancer Intervention:   Drug: rhPSMA-7.3 (18F) Injection Sponsor:   Blue Earth Diagnostics Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
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Source: Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
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Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
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