Mild hypothermia alleviates diabetes aggravated cerebral ischemic injury via activating autophagy and inhibiting pyroptosis.

In conclusion, mild hypothermia alleviated diabetes aggravated cerebral ischemic injury via activating autophagy and inhibiting pyroptosis. PMID: 31082455 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research

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(University of South Australia) Barbecued, stir-fried or roasted, there's no doubt that Aussies love their meat. Consuming on average nearly 100 kilograms of meat per person per year, Australians are among the top meat consumers worldwide. But with statistics showing that most Australians suffer from a poor diet, and red meat production adding to greenhouse-gas emissions, finding a balance between taste preferences, environmental protection, and health benefits is becoming critical.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 7 December 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Jennifer R. Snaith, Deborah J. Holmes-Walker, Jerry R. GreenfieldIndividuals with type 1 diabetes (T1D) frequently fail to achieve glycemic goals and have excess cardiovascular risk and premature death. Adjunctive agents may play a role in reducing morbidity, mortality, and the adverse sequelae of insulin treatment. A surge in type 2 diabetes drug development has revealed agents with benefits beyond glucose lowering, including cardiovascular risk reduction. Could these benefits translate to T1D? Specific trials for T...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
AbstractThe age-performance relationship describes changes in the organism ’s structural and functional capabilities over the course of the lifespan. The typical, empirical pattern is an asymmetrical inverted-U shape association with peak capacity occurring early in life. This process is well described in the literature, with an increasing interest in features that chara cterize this pattern, such as the rate of growth, age of peak performance, and rate of decline with aging. This is usually examined in cohorts of individuals followed over time with repeat assessments of physical or cognitive abilities. This framewor...
Source: Archives of Public Health - Category: International Medicine & Public Health Source Type: research
The objective of the work was to develop the marine-derived polysaccharides attenuating 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), and as prospective natural anti-dyslipidemic leads. Physical and chromatographic purification methods were used to isolate the polygalactofucan from the marine macroalgaSargassum wightii andβ-(2-deoxy)-amino-substituted glucopyrananan from a marine crustacean. Glycosidic linkage analysis by the process of methylation was used for structural elucidation of the polygalactofucan, and the methylated and partially methylated alditol acetates were characterized using extensive spectroscop...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
AbstractKetone bodies (KB) provide an alternative energy source and uniquely modulate substrate metabolism during endurance exercise. Nutritional ketosis (blood KBs  >  0.5 mM) can be achieved within minutes via exogenous ketone supplementation or days-to-weeks via conforming to a very low-carbohydrate, ketogenic diet (KD). In contrast to short-term (  3 weeks) leads to a state of keto-adaptation. However, despite elevating blood KBs to similar concentrations, exogenous ketone supplementation and keto-adaptation are not similar metabolic states as they elicit diverse and distinct effects o...
Source: Sports Medicine - Category: Sports Medicine Source Type: research
This study demonstrated that the insoluble fiber dissociated from edible mushroom byproducts has good potential for producing the edible films.
Source: Journal of Food Engineering - Category: Food Science Source Type: research
(Natural News) Going on a keto diet can be difficult, especially if you love eating high-carb foods. But by making some healthy swaps, you can occasionally enjoy keto-friendly treats like keto bread. How can you make bread keto-friendly? The ketogenic diet is a low-carb, high-fat and moderate-protein eating plan. Going keto offers several health benefits, such as:...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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