MEIS1 knockdown may promote differentiation of esophageal squamous carcinoma cell line KYSE ‐30

ConclusionMEIS1 gene silencing in KYSE ‐30 cells increased expression of epithelial markers and decreased expression of epithelial‐mesenchymal transition (EMT) markerTWIST1. It may highlight the role ofMEIS1 in differentiation process of KYSE ‐30 cells. These results may confirm thatMEIS1 silencing promotes differentiation and decreases EMT capability of ESC cell line KYSE ‐30.

Source: Molecular Genetics & Genomic Medicine - May 13, 2019 Category: Genetics & Stem Cells Authors: Reihaneh Alsadat Mahmoudian, Bahareh Bahadori, Abolfazl Rad, Mohammad Reza Abbaszadegan, Mohammad Mahdi Forghanifard Tags: ORIGINAL ARTICLE Source Type: research